Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Restoration of cytomegalovirus antigen presentation by gamma interferon combats viral escape

1 Jan 1994

Abstract excerpt

An immediate-early protein of murine cytomegalovirus (MCMV), pp89, elicits an immunodominant and protective major histocompatibility complex (MHC) class I Ld-restricted CD8+ T-lymphocyte response. Remarkably, presentation of the naturally processed peptide of pp89, the nonapeptide YPHFMPTNL, is abolished during permissive MCMV infection in vitro. This defect in pp89 presentation is due to the expression of MCMV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8254740
DOI: 10.1128/jvi.68.1.289-297.1994

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Restoration of cytomegalovirus antigen presentation by gamma interferon combats viral escapePMID 8254740Read ↗

Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product.Semantic proximity Read ↗

Processing and Presentation of Murine Cytomegalovirus pORF<i>m164</i>-Derived Peptide in Fibroblasts in the Face of All Viral Immunosubversive Early Gene FunctionsSemantic proximity Read ↗

Viral interference with antigen presentation to CD8+ T cells: lessons from cytomegalovirus.Semantic proximity Read ↗

Cytomegalovirus immune evasion sets the functional avidity threshold for protection by CD8 T cellsSemantic proximity Read ↗

Cytomegalovirus Misleads Its Host by Priming of CD8 T Cells Specific for an Epitope Not Presented in Infected TissuesSemantic proximity Read ↗

Suppression of Murine Cytomegalovirus (MCMV) Replication with a DNA Vaccine Encoding MCMV M84 (a Homolog of Human Cytomegalovirus pp65)Semantic proximity Read ↗

Identification of an atypical CD8 T cell epitope encoded by murine cytomegalovirus ORF-M54 gaining dominance after deletion of the immunodominant antiviral CD8 T cell specificities.Semantic proximity Read ↗

Processing and MHC class I presentation of human cytomegalovirus pp65-derived peptides persist despite gpUS2–11-mediated immune evasionSemantic proximity Read ↗

Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection.Semantic proximity Read ↗

A Dominant Role for the Immunoproteasome in CD8+ T Cell Responses to Murine CytomegalovirusSemantic proximity Read ↗

Murine cytomegalovirus degrades MHC class II to colonize the salivary glandsSemantic proximity Read ↗

The context of gene expression defines the immunodominance hierarchy of cytomegalovirus antigens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.