Article
Viral interference with antigen presentation to CD8+ T cells: lessons from cytomegalovirus.
Viral immunology - 1 Jan 2005
Pinto Amelia K, Hill Ann B
Abstract excerpt
Cytomegaloviruses (CMV), in common with other Herpesviruses, establish lifelong persistence in their hosts. These highly host-specific viruses each encode viral genes that interfere with antigen presentation to CD8+ T cells, although the molecular mechanisms by which this end is achieved differ for human and murine CMVs. In each case, there has been a presumption that these genes are necessary for virus...
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