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Article

Cytomegalovirus (CMV) IE1- and pp65-specific CD8+ T cell responses broaden over time after primary CMV infection in infants.

The Journal of infectious diseases - 15 Jun 2007

Gibson Laura, Dooley Sheryl, Trzmielina Sonia, Somasundaran Mohan, Fisher Donna, Revello Maria Grazia, Luzuriaga Katherine

Abstract excerpt

Cytomegalovirus (CMV) infection remains a significant cause of morbidity and mortality in young children. We have previously shown that CD8+ T cell responses to CMV pp65 or IE1 protein were readily detectable in children with congenital or postnatal CMV infection. Here, we have further characterized the evolution of the peptide specificity of these responses in 7 infants<6 months of age at the start of the study....

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Share to Antigens, Viral
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytomegalovirus

Share to Cytomegalovirus Infections

Share to Immediate-Early Proteins

Share to Leukocytes, Mononuclear

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Source

Identifiers

PMID: 17492595
DOI: 10.1086/518042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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