Article
T-cell alpha beta + and gamma delta + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium.
Proceedings of the National Academy of Sciences of the United States of America - 15 Oct 1996
Roberts S J, Smith A L, West A B, Wen L, Findly R C, Owen M J, Hayday A C
Abstract excerpt
Vertebrate immune systems contain T cells bearing either alpha beta or gamma delta T-cell antigen receptors (TCRs). alpha beta T cells perform all well-characterized T-cell effector functions, while the biological functions of gamma delta + cells remain unclear. Of particular interest is the role of gamma delta + cells during epithelial infections, since gamma delta + cells are commonly abundant within epithelia....
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