Article
T-cell alpha beta + and gamma delta + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium.
Proceedings of the National Academy of Sciences of the United States of America - 15 Oct 1996
Roberts S J, Smith A L, West A B, Wen L, Findly R C, Owen M J, Hayday A C
Abstract excerpt
Vertebrate immune systems contain T cells bearing either alpha beta or gamma delta T-cell antigen receptors (TCRs). alpha beta T cells perform all well-characterized T-cell effector functions, while the biological functions of gamma delta + cells remain unclear. Of particular interest is the role...
Topics
- Adoptive Transfer
- Animals
- CD4-Positive T-Lymphocytes
- Coccidiosis
- Eimeria
- Gastrointestinal Hemorrhage
- Intestinal Diseases
- Intestinal Mucosa
- Intestine, Small
- Lymph Nodes
- Lymphocyte Transfusion
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains