Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization.

doi:10.1084/jem.172.1.239

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Article

Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization.

The Journal of experimental medicine - 1 Jul 1990

Bandeira A, Mota-Santos T, Itohara S, Degermann S, Heusser C, Tonegawa S, Coutinho A

Abstract excerpt

Using monoclonal antibodies identifying all gamma/delta and alpha/beta T cell receptors in cytofluorometric analysis, we have compared the composition of intestinal intraepithelial lymphocytes (i-IEL) in euthymic and athymic germ-free (GF) and conventional (SPF) mice. The results show a marked in...

Topics

Animals
Antibodies, Monoclonal
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
Cell Separation
Epithelium
Female
Flow Cytometry
Germ-Free Life
Intestines
Male
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Phenotype

Receptors, Antigen, T-Cell

Receptors, Antigen, T-Cell, alpha-beta

Receptors, Antigen, T-Cell, gamma-delta

Specific Pathogen-Free Organisms

Source

Open in PubMed Open full text

Identifiers

PMID: 2141628
DOI: 10.1084/jem.172.1.239
PMCID: PMC2188170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2141628-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization.PMID 2141628Read ↗

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