Article
A critical role of T-cell receptor gamma/delta cells in antibacterial protection in mice early in life.
Hepatology (Baltimore, Md.) - 1 Apr 2001
Emoto M, Miyamoto M, Emoto Y, Zerrahn J, Kaufmann S H
Abstract excerpt
Although it is generally assumed that T-cell receptor (TCR) gamma/delta cells participate in protection against intracellular microbial pathogens, their impact remains controversial. In our study, young (14-day-old) mice lacking TCRgamma/delta cells were far more susceptible to Listeria monocytogenes than wild-type (WT) mice of the same age. The number of interferon gamma (IFN-gamma) producers responsible for...
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