Article
Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen.
Nature - 2 Sept 1993
Mombaerts P, Arnoldi J, Russ F, Tonegawa S, Kaufmann S H
Abstract excerpt
Several bacterial pathogens of medical importance are able to persist and replicate inside host mononuclear phagocytes. Protective immunity depends on specific T lymphocytes that induce granulomatous lesions at the sites of bacterial multiplication. Listeria monocytogenes is an intracellular pathogen that replicates inside mononuclear phagocytes and hepatocytes of mice. Invasion from the phagosomal compartment...
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