Article
Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen.
Nature - 2 Sept 1993
Mombaerts P, Arnoldi J, Russ F, Tonegawa S, Kaufmann S H
Abstract excerpt
Several bacterial pathogens of medical importance are able to persist and replicate inside host mononuclear phagocytes. Protective immunity depends on specific T lymphocytes that induce granulomatous lesions at the sites of bacterial multiplication. Listeria monocytogenes is an intracellular path...
Topics
- Animals
- Bacterial Vaccines
- Female
- Hypersensitivity, Delayed
- Immunity, Innate
- Interferon-gamma
- Listeriosis
- Liver
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mutation
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta
- T-Lymphocyte Subsets