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Article

Poorly repaired mismatches in heteroduplex DNA are hyper-recombinagenic in Saccharomyces cerevisiae.

Genetics - 1 Feb 1996

Manivasakam P, Rosenberg S M, Hastings P J

Abstract excerpt

In yeast meiotic recombination, alleles used as genetic markers fall into two classes as regards their fate when incorporated into heteroduplex DNA. Normal alleles are those that form heteroduplexes that are nearly always recognized and corrected by the mismatch repair system operating in meiosis. High PMS (postmeiotic segregation) alleles form heteroduplexes that are inefficiently mismatch repaired. We report...

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Identifiers

PMID: 8852840
DOI: 10.1093/genetics/142.2.407
PMCID: PMC1206975

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Source receipt: pubmed, retrieved 7 Sept 2026.

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