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Article

Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Feb 1991

Detloff P, Sieber J, Petes T D

Abstract excerpt

Heteroduplexes formed between DNA strands derived from different homologous chromosomes are an intermediate in meiotic crossing over in the yeast Saccharomyces cerevisiae and other eucaryotes. A heteroduplex formed between wild-type and mutant genes will contain a base pair mismatch; failure to repair this mismatch will lead to postmeiotic segregation (PMS). By analyzing the frequency of PMS for various mutant...

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Identifiers

PMID: 1990280
DOI: 10.1128/mcb.11.2.737-745.1991
PMCID: PMC359725

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