Article
Genome-wide survey of post-meiotic segregation during yeast recombination.
Genome biology - 1 Jan 2011
Mancera Eugenio, Bourgon Richard, Huber Wolfgang, Steinmetz Lars M
Abstract excerpt
BACKGROUND: When mismatches in heteroduplex DNA formed during meiotic recombination are left unrepaired, post-meiotic segregation of the two mismatched alleles occurs during the ensuing round of mitosis. This gives rise to somatic mosaicism in multicellular organisms and leads to unexpected allelic combinations among progeny. Despite its implications for inheritance, post-meiotic segregation has been studied at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
