Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The macrolide-lincosamide-streptogramin B resistance phenotypes characterized by using a specifically deleted, antibiotic-sensitive strain of Streptomyces lividans.

Antimicrobial agents and chemotherapy - 1 Mar 1996

Pernodet J L, Fish S, Blondelet-Rouault M H, Cundliffe E

Abstract excerpt

Genes conferring resistance to macrolide, lincosamide, and streptogramin B (MLS) antibiotics via ribosomal modification are widespread in bacteria, including clinical isolates and MLS-producing actinomycetes. Such erm-type genes encode enzymes that mono- or dimethylate residue A-2058 of 23S rRNA. The different phenotypes resulting from monomethylation (MLS-I phenotype, conferred by erm type I genes) or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to Genes, Bacterial

Share to Microbial Sensitivity Tests

Share to Phenotype

Share to Plasmids

Share to RNA, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 8851574
DOI: 10.1128/AAC.40.3.581
PMCID: PMC163161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The macrolide-lincosamide-streptogramin B resistance phenotypes characterized by using a specifically deleted, antibiotic-sensitive strain of Streptomyces lividans.PMID 8851574Read ↗

Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics.Semantic proximity Read ↗

Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Regulation of the macrolide resistance ABC-F translation factor MsrDSemantic proximity Read ↗

Regulation of the macrolide resistance ABC-F translation factor MsrDSemantic proximity Read ↗

Inactivation of a purine biosynthesis repressor promotes ribosome synthesis to overcome antibiotic stress.Semantic proximity Read ↗

Macrolide antibiotic interaction and resistance on the bacterial ribosome.Semantic proximity Read ↗

Molecular cloning and characterization of two lincomycin-resistance genes, lmrA and lmrB, from Streptomyces lincolnensis 78-11.Semantic proximity Read ↗

Structural studies on ribosomes of differentially macrolide-resistant Staphylococcus aureus strainsSemantic proximity Read ↗

Activity of the ketolide telithromycin is refractory to Erm monomethylation of bacterial rRNA.Semantic proximity Read ↗

Ketolide resistance in Streptococcus pyogenes correlates with the degree of rRNA dimethylation by ErmSemantic proximity Read ↗

Methylation of 23S ribosomal RNA due to carB, an antibiotic-resistance determinant from the carbomycin producer, Streptomyces thermotolerans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.