Article

Regulation of the macrolide resistance ABC-F translation factor MsrD

2021-11-29

Abstract excerpt

<h4>SUMMARY</h4> A ntibiotic r esistance ABC-Fs (ARE ABC-Fs) are translation factors currently proliferating among human pathogens that provide resistance against clinically important ribosome-targeting antibiotics. Here, we combine genetic and structural approaches to determine the regulation of streptococcal ARE ABC-F gene msrD in response to macrolide exposure and also demonstrate that MsrD twin-ATPase site...

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Literature Corpus work: 9b1ab29b-2359-5567-8015-24137b56b86c
DOI: 10.1101/2021.11.29.470318

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