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Article

Deletion and interallelic complementation analysis of Steel mutant mice.

Genetics - 1 Mar 1996

Bedell M A, Cleveland L S, O'Sullivan T N, Copeland N G, Jenkins N A

Abstract excerpt

Mutations at the Steel (Sl) locus produce pleiotropic effects on viability as well as hematopoiesis, pigmentation and fertility. Several homozygous viable Sl alleles have previously been shown to contain either structural alterations in mast cell growth factor (Mgf) or regulatory mutations that affect expression of the Mgf gene. More severe Sl alleles cause lethality to homozygous embryos and all lethal Sl...

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Identifiers

PMID: 8849899
DOI: 10.1093/genetics/142.3.935
PMCID: PMC1207030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletion and interallelic complementation analysis of Steel mutant mice.PMID 8849899Read ↗

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Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.Semantic proximity Read ↗

Developmental abnormalities in Steel17H mice result from a splicing defect in the steel factor cytoplasmic tail.Semantic proximity Read ↗

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles.Semantic proximity Read ↗

Steel factor and c-kit protooncogene: genetic lessons in signal transduction.Semantic proximity Read ↗

DNA rearrangements located over 100 kb 5' of the Steel (Sl)-coding region in Steel-panda and Steel-contrasted mice deregulate Sl expression and cause female sterility by disrupting ovarian follicle development.Semantic proximity Read ↗

Detection of a point mutation (A to G) in exon 5 of the murine Mgf gene defines a novel allele at the Steel locus with a weak phenotype.Semantic proximity Read ↗

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Sl/Sld hematopoietic progenitors are deficient in situ.Semantic proximity Read ↗

A rare complex DNA rearrangement in the murine Steel gene results in exon duplication and a lethal phenotype.Semantic proximity Read ↗

Interallelic complementation at the mouse Mitf locus.Semantic proximity Read ↗

Differential activity of maternally and paternally derived chromosome regions in mice.Semantic proximity Read ↗

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