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Article

Interallelic complementation at the mouse Mitf locus.

Genetics - 1 Jan 2003

Steingrímsson Eiríkur, Arnheiter Heinz, Hallsson Jón Hallsteinn, Lamoreux M Lynn, Copeland Neal G, Jenkins Nancy A

Abstract excerpt

Mutations at the mouse microphthalmia locus (Mitf) affect the development of different cell types, including melanocytes, retinal pigment epithelial cells of the eye, and osteoclasts. The MITF protein is a member of the MYC supergene family of basic-helix-loop-helix-leucine-zipper (bHLHZip) transcription factors and is known to regulate the expression of cell-specific target genes by binding DNA as homodimer or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12586714
DOI: 10.1093/genetics/163.1.267
PMCID: PMC1462411

Genes

MITF
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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