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Article

Sl/Sld hematopoietic progenitors are deficient in situ.

Experimental hematology - 1 Feb 1994

Barker J E

Abstract excerpt

The hematopoietic microenvironment in Steel mutant mice does not support erythropoiesis, megakaryocytopoiesis, or mast cell generation. The question of whether Steel hematopoietic progenitors are present in normal numbers has never been convincingly addressed. In this report, Sl/Sld marrow cells were assessed for long-term competitive repopulation ability in vivo and for short-term growth in vitro. In vivo...

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PMID: 7507859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sl/Sld hematopoietic progenitors are deficient in situ.PMID 7507859Read ↗

Deletion and interallelic complementation analysis of Steel mutant mice.Semantic proximity Read ↗

Mouse hematopoietic stem cells and the interaction of c-kit receptor and steel factor.Semantic proximity Read ↗

Clonogenic mast cell progenitors and their excess numbers in chimeric BALB/c mice with inactivated GATA-1.Semantic proximity Read ↗

Adult scl+/+ murine hemangioblasts persist in allogeneic mutant blastocysts but fail to rescue the scl-/- phenotype.Semantic proximity Read ↗

Development of hematopoietic cells lacking transcription factor GATA-1Semantic proximity Read ↗

Characterization of spleen colonies derived from mice with mutations at the W locus.Semantic proximity Read ↗

Anemia and mast cell depletion in mutant rats that are homozygous at "white spotting (Ws)" locus.Semantic proximity Read ↗

The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus.Semantic proximity Read ↗

Adhesion of mouse mast cells to fibroblasts: adverse effects of steel (Sl) mutation.Semantic proximity Read ↗

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