Article
Effect of apolipoprotein E genotype on Alzheimer's disease neuropathology in a cohort of elderly Norwegians.
Neuroscience letters - 1 Dec 1995
Morris C M, Benjamin R, Leake A, McArthur F K, Candy J M, Ince P G, Torvik A, Bjertness E, Edwardson J A
Abstract excerpt
A cohort of elderly Norwegians dying in nursing homes in the Oslo region have been genotyped for the Apolipoprotein E (ApoE) gene. Alzheimer's disease (AD) cortical neuropathology and clinical evidence of dementia were used to assign cases without evidence of other confounding neuropathology. Senile plaque (SP) and neurofibrillary tangle (NFT) densities in frontal, temporal and parietal cortex were then...
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