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Article

Clinical and neuropathological correlates of apolipoprotein E genotype in dementia with Lewy bodies.

Dementia and geriatric cognitive disorders - 1 Jan 2002

Singleton Andrew B, Wharton Anna, O'Brien Kirsty K, Walker Matthew P, McKeith Ian G, Ballard Clive G, O'Brien John, Perry Robert H, Ince Paul G, Edwardson James A, Morris Christopher M

Abstract excerpt

Dementia with Lewy bodies (DLB) represents the second commonest cause of dementia in the elderly following Alzheimer's disease (AD). Whilst the presence of Lewy bodies is essential, DLB shares with AD the presence of senile plaques (SP), but neurofibrillary tangles (NFT) are not a necessary feature. The apolipoprotein E (APO E) epsilon4 allele is the most consistently associated genetic risk factor for AD and has...

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PMID: 12411758
DOI: 10.1159/000066022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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