Article
Regulation of HIV-1 gene expression by NF-IL6.
Journal of molecular biology - 27 Sept 1996
Tesmer V M, Bina M
Abstract excerpt
Previous studies have shown that in human T-cells (Jurkat) and hepatoma cells (HepG2), exogenous NF-IL6 can activate HIV-1 gene expression even in the absence of its consensus binding elements in the viral long terminal repeat (LTR). To identify the LTR elements that mediate this response, we have analysed constructs containing mutated and deleted LTR sequences. We have also examined heterologous plasmids to...
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