Article
Transcriptional regulation of HIV-1 LTR during antigen-dependent activation of primary T cells by dendritic cells.
Journal of leukocyte biology - 1 Mar 2000
Tsunetsugu-Yokota Y, Kato T, Yasuda S, Matsuda Z, Suzuki Y, Koyanagi Y, Yamamoto N, Akagawa K, Cho M W, Takemori T
Abstract excerpt
Numerous factors are known to bind human immunodeficiency virus (HIV) long terminal repeat (LTR) and activate viral transcription, but little is known as to how they function in naturally activated T cells and to what extent their binding is relevant to HIV replication in vivo. To characterize the HIV LTR-binding factors responsible for antigen-dependent activation of HIV, we examined replication of LTR mutant...
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