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Article

The HIV-1 regulatory protein Nef has a specific function in viral expression in a murine macrophage cell line.

Journal of leukocyte biology - 1 Sept 1994

Murphy K M, Sweet M J, Hume D A

Abstract excerpt

Expression of reporter genes under the control of the HIV-1 long terminal repeat (LTR) was up-regulated in the murine macrophage cell line RAW264 by cotransfection of a plasmid coding for the viral regulatory protein Nef. To determine if a discrete section of the LTR was exclusively responsive to Nef, a series of promoters was produced by successive 5' deletions from the LTR up to the boundary of the enhancer...

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Identifiers

PMID: 8083602
DOI: 10.1002/jlb.56.3.294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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