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Article

Fluorescence-based polymerase chain reaction-single-strand conformation polymorphism analysis of p53 gene by capillary electrophoresis.

Journal of chromatography. A - 13 Sept 1996

Katsuragi K, Kitagishi K, Chiba W, Ikeda S, Kinoshita M

Abstract excerpt

Mutation of the p53 gene plays an important role in neoplastic progression in human tumorigenesis. Polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) techniques are now available for the detection of point mutations. The original method using polyacrylamide gel electroph...

Topics

Alleles
Automation
Base Sequence
DNA Primers
DNA, Neoplasm
Electrophoresis, Capillary
Electrophoresis, Polyacrylamide Gel
Genes, p53
Humans
Lung Neoplasms
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single-Stranded Conformational

Sequence Analysis, DNA

Spectrometry, Fluorescence

Source

Identifiers

PMID: 8843680
DOI: 10.1016/0021-9673(96)00397-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8843680-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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