Article
The nanomelic mutation in the aggrecan gene is expressed in chick chondrocytes and neurons.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Jun 1996
Domowicz M, Krueger R C, Li H, Mangoura D, Vertel B M, Schwartz N B
Abstract excerpt
We have established the presence of at least two large chondroitin sulfate proteoglycans in the developing chick brain, one that reacts exclusively with HNK-1, a carbohydrate epitope found on several neural specific molecules, and one that reacts with S103L, a defined peptide epitope in the CS-2 domain of the cartilage-specific chondroitin sulfate proteoglycan (CSPG), aggrecan. In order to determine the...
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