Article
Aggrecan regulates telencephalic neuronal aggregation in culture.
Brain research. Developmental brain research - 12 Jul 2003
Domowicz Miriam S, Mangoura Dimitra, Schwartz Nancy B
Abstract excerpt
Proteoglycans have been suggested to play roles in pattern formation in the developing central nervous system. In the chick embryo, aggrecan, a chondroitin sulfate proteoglycan, has a regionally-specific and developmentally-regulated expression profile. Telencephalic neuronal cultures, when aggregated, exhibit aggrecan expression patterns comparable to those observed in vivo. The chicken mutation nanomelia...
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