Article
Reduced epidermal expression of a PG-M/versican-like proteoglycan in embryos of the white mutant axolotl.
Experimental cell research - 10 Oct 1997
Stigson M, Löfberg J, Kjellén L
Abstract excerpt
Axolotl embryos have previously been used to study neural crest cell migration. In embryos of the normal wild type, neural crest cells migrate subepidermally to form pigment cells. In the trunk of the white mutant embryo, these cells are unable to migrate, possibly due to an inherited delay in the maturation of the local extracellular matrix. The present investigation reveals a reduced incorporation of...
Topics
- Albinism
- Ambystoma mexicanum
- Animals
- Cell Movement
- Chondroitin Sulfate Proteoglycans
- Epidermal Cells
- Epidermis
- Epithelial Cells
- Gene Expression Regulation, Developmental
- Lectins, C-Type
- Mutation
- RNA, Messenger
- Sulfates
- Sulfur Radioisotopes
- Versicans
