Article
Nanomelic chondrocytes synthesize, but fail to translocate, a truncated aggrecan precursor.
Journal of cell science - 1 Mar 1993
Vertel B M, Walters L M, Grier B, Maine N, Goetinck P F
Abstract excerpt
Cartilage extracellular matrix (ECM) is composed primarily of type II collagen and large, link stabilized aggregates of hyaluronic acid and chondroitin sulfate proteoglycan (aggrecan). Maturation and function of these complex macromolecules are dependent upon sequential processing events which oc...
Topics
- Aggrecans
- Ammonium Chloride
- Animals
- Cartilage
- Cells, Cultured
- Chick Embryo
- Chondroitin Sulfate Proteoglycans
- Cold Temperature
- Cytoplasm
- Extracellular Matrix
- Extracellular Matrix Proteins
- Golgi Apparatus
- Lectins, C-Type
- Limb Deformities, Congenital
- Microscopy, Immunoelectron
- Mutation
- Procollagen
- Protein Precursors
