Article
Expression of the murine wild-type tyrosinase gene in transgenic rabbits.
Transgenic research - 1 Nov 1996
Aigner B, Besenfelder U, Seregi J, Frenyo L V, Sahin-Toth T, Brem G
Abstract excerpt
The tyrosinase gene is known to be essential for melanization and has been shown to rescue pigmentation in albino mice. Previously we have described the strict copy-number-dependent expression of a murine wild-type tyrosinase gene construct over several generations in transgenic mice. In this stu...
Topics
- Animals
- Animals, Genetically Modified
- Female
- Founder Effect
- Gene Expression Regulation
- Gene Frequency
- Genetic Markers
- Homozygote
- Mice
- Monophenol Monooxygenase
- Pedigree
- Phenotype
- Pregnancy
- Rabbits
- Recombinant Proteins
