Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stable long-term germ-line transmission of transgene integration sites in mice.

Transgenic research - 1 Feb 1999

Aigner B, Fleischmann M, Müller M, Brem G

Abstract excerpt

Transgenic mice provide a valuable tool in all fields of basic and applied biological and medical research. In this study, we describe the fate of integrated transgenes in the mammalian host genome over a large number of generations. The stability of the germ-line transmission of integrated tyrosinase transgene copies was monitored up to generation F20 in a large number of individuals from seven transgenic mouse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Phenotype
Share to Breeding
Share to Germ Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homozygote

Share to Mice, Transgenic

Share to Monophenol Monooxygenase

Share to Transgenes

Source

Identifiers

PMID: 10399363
DOI: 10.1023/a:1008824028100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stable long-term germ-line transmission of transgene integration sites in mice.PMID 10399363Read ↗

Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesisSemantic proximity Read ↗

Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells.Semantic proximity Read ↗

Expression of the murine wild-type tyrosinase gene in transgenic rabbits.Semantic proximity Read ↗

Analysis of the transgene insertion pattern in a transgenic mouse strain using long-read sequencing.Semantic proximity Read ↗

Generating <i>in vivo</i> somatic mouse mosaics with locus-specific, stably-integrated transgenic elementsSemantic proximity Read ↗

Rapid and precise genotyping of transgene zygosity in mice using an allele-specific method.Semantic proximity Read ↗

Long-term (10-year) monitoring of transposon-mediated transgenic cattle.Semantic proximity Read ↗

Chicken beta-globin 5'HS4 insulators function to reduce variability in transgenic founder mice.Semantic proximity Read ↗

Efficient generation of transgenic mice with intact yeast artificial chromosomes by intracytoplasmic sperm injection.Semantic proximity Read ↗

Sequencing two Tyr::CreERT2 transgenic mouse lines.Semantic proximity Read ↗

Genomic analysis of a novel spontaneous albino C57BL/6N mouse strain.Semantic proximity Read ↗

Identifying and genotyping transgene integration loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.