Article
What causes p53 mutations in patients with lung cancer?
Oncology reports - 1 Jan 2000
Sekine I, Shao G G, Fahey M, Kodama T, Nagai K, Kuriyama T
Abstract excerpt
We studied the association between occurrence of p53 mutations and both smoking history and family history of cancer (FH) in 109 lung cancer patients using the logistic regression model. A dose-response relationship between smoking defined as pack-years smoked (PY) and p53 mutations was clearly d...
Topics
- Adenocarcinoma
- Adult
- Aged
- Carcinoma, Adenosquamous
- Carcinoma, Large Cell
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Family
- Female
- Genes, p53
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Multivariate Analysis
- Mutation
- Necrosis
- Odds Ratio