[p53 alterations in human lung cancer and their correlation with clinicopathological features and prognosis].

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Article

[p53 alterations in human lung cancer and their correlation with clinicopathological features and prognosis].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Aug 1998

Zhang J, Zheng J, Fang W

Abstract excerpt

OBJECTIVE: To investigate p53 protein accumulations and p53 mutations in squamous cell carcinoma and adenocarcinoma of the lung and their correlation with clinicopathological features and prognosis. METHODS: Immunohistochemistry (LSAB) and non-isotopic PCR-SSCP were used to detect p53 abnormalities in lung cancer. RESULTS: The general positive rates for immunohistochemistry using anti-p53 monoclonal antibody Do-7...

Topics

Adenocarcinoma
Adult
Aged
Carcinoma, Squamous Cell
Female
Follow-Up Studies
Genes, p53
Humans
Lung Neoplasms
Lymphatic Metastasis
Male
Middle Aged
Mutation
Neoplasm Staging
Survival Rate
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 11244999

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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