Article
[p53 alterations in human lung cancer and their correlation with clinicopathological features and prognosis].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Aug 1998
Zhang J, Zheng J, Fang W
Abstract excerpt
OBJECTIVE: To investigate p53 protein accumulations and p53 mutations in squamous cell carcinoma and adenocarcinoma of the lung and their correlation with clinicopathological features and prognosis. METHODS: Immunohistochemistry (LSAB) and non-isotopic PCR-SSCP were used to detect p53 abnormalities in lung cancer. RESULTS: The general positive rates for immunohistochemistry using anti-p53 monoclonal antibody Do-7...
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