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Article

The incidence of the gene for thermolabile methylene tetrahydrofolate reductase in African Americans.

Thrombosis research - 15 Jul 1996

McAndrew P E, Brandt J T, Pearl D K, Prior T W

Abstract excerpt

Increased levels of homocysteine have been linked to both arterial and venous thromboembolic problems (1,2). Homocystinuria is a relatively rare disorder caused by a deficiency of cystathione synthase and is characterized by markedly increased levels of homocysteine and premature vascular disease (3-5). Epidemiological studies have suggested that mild elevations of homocysteine are also associated with vascular...

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Source

Identifiers

PMID: 8837319
DOI: 10.1016/0049-3848(96)00121-1

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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The incidence of the gene for thermolabile methylene tetrahydrofolate reductase in African Americans.PMID 8837319Read ↗

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The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia.Semantic proximity Read ↗

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