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Article

Low frequency of mutated methylenetetrahydrofolate reductase 677C-->T and 1298A-->C genetics single nucleotide polymorphisms (SNPs) in Sub-Saharan populations.

Clinical chemistry and laboratory medicine - 1 Aug 2003

Adjalla Charles E, Amouzou Emile K, Sanni Ambaliou, Abdelmouttaleb Idrissia, Chabi Nicodème W, Namour Fares, Soussou Batoma, Guéant Jean-Louis

Abstract excerpt

5,10-Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR) are two of the key enzymes in the folate/vitamin B12-dependent remethylation of homocysteine to methionine. The frequencies of MTHFR single nucleotide polymorphisms (SNPs), 677C-->T, 1298A-->C, 1317T-->C and of MTR, 27...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Africa South of the Sahara

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Homocysteine

Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 12964809
DOI: 10.1515/CCLM.2003.158

Genes

MTHFR
MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12964809-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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