Article
Thermolabile methylenetetrahydrofolate reductase polymorphism (C677T) and total homocysteine concentration among African-American and white women.
Ethnicity & disease - 1 Jan 1998
Giles W H, Kittner S J, Ou C Y, Croft J B, Brown V, Buchholz D W, Earley C J, Feeser B R, Johnson C J, Macko R F, McCarter R J, Price T R, Sloan M A, Stern B J, Wityk R J, Wozniak M A, Stolley P D
Abstract excerpt
A polymorphism associated with a thermolabile variant (C677T) of the enzyme methylenetetrahydrofolate reductase has been associated with both elevated total homocysteine (tHcy) levels and risk for cardiovascular disease. Data from the Stroke Prevention in Young Women Study were used to determine the prevalence of the C677T genotype and to assess whether environmental factors modified the association between...
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