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Article

Polymorphisms of ethanol-oxidizing enzymes in alcoholics with inactive ALDH2.

Human genetics - 1 Apr 1996

Higuchi S, Muramatsu T, Matsushita S, Murayama M, Hayashida M

Abstract excerpt

Inactive aldehyde dehydrogenase-2 (ALDH2) is a well-known biological deterrent of heavy drinking among Asians, although some individuals who have inactive ALDH2 do become alcoholics. Unknown biological mechanisms facilitating the development of the disease may operate in such a way that these individuals overcome adverse reactions, or they may lower the intensity of the reactions. To examine our hypothesis that...

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Source

Identifiers

PMID: 8834237
DOI: 10.1007/BF02267061

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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