ahpC, a gene involved in isoniazid resistance of the Mycobacterium tuberculosis complex.

doi:10.1046/j.1365-2958.1996.449980.x

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Article

ahpC, a gene involved in isoniazid resistance of the Mycobacterium tuberculosis complex.

Molecular microbiology - 1 Mar 1996

Wilson T M, Collins D M

Abstract excerpt

A gene conferring low-level isoniazid (INH) resistance on Mycobacterium smegmatis was isolated from a cosmid library of the genome of an INH-resistant Mycobacterium bovis strain. The gene had good homology with ahpC, the product of which is a subunit of alkyl hydroperoxide reductase, and also wit...

Topics

Amino Acid Sequence
Animals
Bacterial Proteins
Base Sequence
DNA, Bacterial
Drug Resistance, Microbial
Genes, Bacterial
Humans
Isoniazid
Molecular Sequence Data
Mutation
Mycobacterium tuberculosis
Oxidoreductases
Peroxidases
Peroxiredoxins
Promoter Regions, Genetic
Sequence Homology, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 8830260
DOI: 10.1046/j.1365-2958.1996.449980.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8830260-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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