Article
Quantitative phenotype analysis for localization and identification of disease-related genes in a complex genetic background.
Ciba Foundation symposium - 1 Jan 1996
Lathrop G M
Abstract excerpt
Results from genetic investigations of blood pressure and other variables in inbred rodent models are reviewed here to illustrate the power of quantitative approaches for the detection of linkage and the ultimate identification of the underlying genes. Different studies-involving angiotensinogen...
Topics
- Animals
- Chromosome Mapping
- Disease Models, Animal
- Genetic Diseases, Inborn
- Genetic Variation
- Humans
- Phenotype
