Article
Genes and hypertension: where we are and where we should go.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2000
Hamet P
Abstract excerpt
Our understanding of the genetics of hypertension is incomplete. A great deal has, however, been learned about the role of several <<candidate>> genes by altering their expression in transgenic and knockout models. Crosses of inbred strains, analyzed in F2 generations, have demonstrated consistent quantitative trait loci, particularly on chromosomes 1, 2 and 10, suggesting significant contributions of some genes...
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