Coabnormal expression of cyclin D1 and p53 protein in human uterine endometrial carcinomas.

doi:10.1002/(SICI)1097-0142(19960915)78:6<1248::AID-CNCR12>3.0.CO;2-0

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Article

Coabnormal expression of cyclin D1 and p53 protein in human uterine endometrial carcinomas.

Cancer - 15 Sept 1996

Nikaido T, Li S F, Shiozawa T, Fujii S

Abstract excerpt

BACKGROUND: In the normal cell cycle, tumor suppressor gene products (p53) and cyclin (cyclin D1) cooperate. Abnormalities in the cooperation of these factors may result in malignant transformation of the cell. Mutant p53 protein overexpression is defined in many human cancers, including endometr...

Topics

Adult
Aged
Carcinoma
Cell Cycle
Cell Transformation, Neoplastic
Coloring Agents
Cyclin D1
Cyclins
Disease Progression
Endometrial Hyperplasia
Endometrial Neoplasms
Endometrium
Female
Gene Expression Regulation, Neoplastic
Humans
Immunohistochemistry
Middle Aged
Mutation

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