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Article

Expression and subcellular localization of cyclin D1 protein in epithelial ovarian tumour cells

12 Nov 1999

Abstract excerpt

The expression of cyclin D1 protein in tumour sections from 81 patients with epithelial ovarian cancer was analysed using immunohistochemistry. The tumours that overexpressed cyclin D1 in more than 10% of neoplastic cells were considered positive. Thus overexpression of cyclin D1 was observed in 72/81 (89%) of the cases examined. Protein was detected in both the nucleus and the cytoplasm in 24/81 (30%) and...

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PMID: 10584879
DOI: 10.1038/sj.bjc.6690826

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