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Article

Redundant cyclin overexpression and gene amplification in breast cancer cells.

1 Feb 1993

Abstract excerpt

Cyclins are prime cell cycle regulators and are central to the control of major check points in eukaryotic cells. The aberrant expressions of two cyclins (i.e., cyclins A and D1) have been observed in some cancers, suggesting they may be involved in loss of growth control. However, in spite of these occasional changes involving only two cyclins, there are no clear connections between general derangements of other...

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Identifiers

PMID: 8430082
DOI: 10.1073/pnas.90.3.1112

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