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Cyclin D1 overexpression in hepatocellular carcinoma

1 Apr 2001

Abstract excerpt

BACKGROUND/AIMS: Cyclin D1 gene amplification and cyclin D1 protein overexpression have been reported in various human tumors, including hepatocellular carcinoma (HCC). However, their significance is still controversial. In the present study, we examined the expression of cyclin D1 and its relationships to p53 and Ki-67 in HCCs. METHODS: The expression and topological distribution of cyclin D1, p53 and Ki-67 in...

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PMID: 11318977
DOI: 10.1034/j.1600-0676.2001.021002089.x

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