Article
Mutations in the basal core promoter and precore/core gene of hepatitis B virus in patients with chronic active but not acute hepatitis B.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Dec 1999
Mayerat C, Mantegani A, Spertini F, Frei P C
Abstract excerpt
Around 5-10% of adults infected with hepatitis B virus (HBV) develop a chronic liver disease such as chronic active hepatitis (CAH), and it is unclear whether the clinical outcome depends solely on the immune response or whether viral factors also play a role. In this study, a search was therefore made for nucleotide mutations in the basic core promoter (BCP) and amino-acid substitutions in the precore/core...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.