Article
Apolipoprotein E in the brain and its role in Alzheimer's disease.
Journal of psychiatry & neuroscience : JPN - 1 Mar 1996
Poirier J
Abstract excerpt
Recent evidence indicates that apolipoprotein E (apoE) plays a central role in the brain response to injury. The coordinated expression of apoE and its main receptor, the apoE/apoB (LDL) receptor, appears to regulate the transport of cholesterol and phospholipids during the different phases of th...
Topics
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Brain
- Cholesterol
- Female
- Hippocampus
- Humans
- Male
- Middle Aged
- Synapses
