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Article

Human type 1 diabetes and the insulin gene: principles of mapping polygenes.

Annual review of genetics - 1 Jan 1996

Bennett S T, Todd J A

Abstract excerpt

We review the strategy used to identify a susceptibility locus (IDDM2) for type 1 (insulin dependent) diabetes mellitus. As type 1 diabetes is becoming the paradigm for dissecting multifactorial disease genetics, the approach described provides important general guidelines for positional cloning of human disease polygenes. Main topics include: (a) historical conspectus of the mapping and identification of...

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PMID: 8982458
DOI: 10.1146/annurev.genet.30.1.343

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INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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