Article
Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene.
Diabetologia - 1 May 1996
Doria A, Lee J, Warram J H, Krolewski A S
Abstract excerpt
An inconsistency has come to light between the conclusion of Lucassen et al. that IDDM2 (11p15.5) must lie within a 4.1 kilobase (kb) segment at the insulin (INS) locus and their own data showing statistically significant associations between insulin-dependent diabetes mellitus (IDDM) and markers...
Topics
- Adult
- Age of Onset
- Case-Control Studies
- Chi-Square Distribution
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Humans
- Insulin
- Insulin-Like Growth Factor II
- Minisatellite Repeats
- Multigene Family
- Polymorphism, Genetic
- Reference Values
- Risk Assessment
- Tyrosine 3-Monooxygenase
- White People
