Article
Clinical symptoms and possible anticipation in a large kindred of familial restless legs syndrome.
Movement disorders : official journal of the Movement Disorder Society - 1 Jul 1996
Trenkwalder C, Seidel V C, Gasser T, Oertel W H
Abstract excerpt
Idiopathic restless legs syndrome (RLS) frequently follows an autosomal dominant inheritance with a variable clinical expressivity of symptoms. We describe the largest German kindred of familial RLS with 20 affected and investigated members in four generations with a variety of clinical symptoms....
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Chromosome Aberrations
- Chromosome Disorders
- Female
- Genes, Dominant
- Genetic Carrier Screening
- Genetic Testing
- Humans
- Male
- Middle Aged
- Neurologic Examination
- Pedigree
- Phenotype
- Restless Legs Syndrome