Depletion in the levels of the release factor eRF1 causes a reduction in the efficiency of translation termination in yeast.

doi:10.1111/j.1365-2958.1996.tb02634.x

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Article

Depletion in the levels of the release factor eRF1 causes a reduction in the efficiency of translation termination in yeast.

Molecular microbiology - 1 Jun 1996

Stansfield I, Eurwilaichitr L, Akhmaloka, Tuite M F

Abstract excerpt

In Saccharomyces cerevisiae, translation termination is mediated by a complex of two proteins, eRF1 and eRF3, encoded by the SUP45 and SUP35 genes, respectively. Mutations in the SUP45 gene were selected which enhanced suppression by the weak ochre (UAA) suppressor tRNA(Ser) SUQ5. In each of four...

Topics

Alleles
Cloning, Molecular
DNA, Fungal
Fungal Proteins
Peptide Termination Factors
Phenotype
Protein Biosynthesis
RNA, Fungal
RNA, Transfer
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Sequence Analysis, DNA
Suppression, Genetic

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Identifiers

PMID: 8809766
DOI: 10.1111/j.1365-2958.1996.tb02634.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8809766-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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