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Article

Depletion in the levels of the release factor eRF1 causes a reduction in the efficiency of translation termination in yeast.

Molecular microbiology - 1 Jun 1996

Stansfield I, Eurwilaichitr L, Akhmaloka, Tuite M F

Abstract excerpt

In Saccharomyces cerevisiae, translation termination is mediated by a complex of two proteins, eRF1 and eRF3, encoded by the SUP45 and SUP35 genes, respectively. Mutations in the SUP45 gene were selected which enhanced suppression by the weak ochre (UAA) suppressor tRNA(Ser) SUQ5. In each of four such allosuppressor alleles examined, an in-frame ochre (TAA) mutation was present in the SUP45 coding region;...

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Source

Identifiers

PMID: 8809766
DOI: 10.1111/j.1365-2958.1996.tb02634.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Depletion in the levels of the release factor eRF1 causes a reduction in the efficiency of translation termination in yeast.PMID 8809766Read ↗

Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae.Semantic proximity Read ↗

Molecular dissection of translation termination mechanism identifies two new critical regions in eRF1.Semantic proximity Read ↗

A conditional-lethal translation termination defect in a sup45 mutant of the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae.Semantic proximity Read ↗

N-terminal extension of Saccharomyces cerevisiae translation termination factor eRF3 influences the suppression efficiency of sup35 mutations.Semantic proximity Read ↗

A mutant allele of the SUP45 (SAL4) gene of Saccharomyces cerevisiae shows temperature-dependent allosuppressor and omnipotent suppressor phenotypes.Semantic proximity Read ↗

N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination.Semantic proximity Read ↗

Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae.Semantic proximity Read ↗

Decoding accuracy in eRF1 mutants and its correlation with pleiotropic quantitative traits in yeast.Semantic proximity Read ↗

Identification of the genes encoding the cytosolic translation release factors from Podospora anserina and analysis of their role during the life cycle.Semantic proximity Read ↗

Regulation of release factor expression using a translational negative feedback loop: a systems analysis.Semantic proximity Read ↗

Polypeptide chain termination in Saccharomyces cerevisiae.Semantic proximity Read ↗

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