Article
A mutant allele of the SUP45 (SAL4) gene of Saccharomyces cerevisiae shows temperature-dependent allosuppressor and omnipotent suppressor phenotypes.
Current genetics - 1 Apr 1995
Stansfield I, Akhmaloka, Tuite M F
Abstract excerpt
Using a plasmid-based termination-read-through assay, the sal4-2 conditional-lethal (temperature-sensitive) allele of the SUP45 (SAL4) gene was shown to enhance the efficiency of the weak ochre suppressor tRNA SUQ5 some 10-fold at 30 degrees C. Additionally, this allele increased the suppressor e...
Topics
- Alleles
- Base Sequence
- Cloning, Molecular
- Genes, Fungal
- Genes, Lethal
- Genes, Suppressor
- Molecular Sequence Data
- Mutation
- Phenotype
- RNA, Transfer, Ser
- Saccharomyces cerevisiae
- Sequence Analysis, DNA
- Suppression, Genetic
- Temperature