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Article

Identification of the genes encoding the cytosolic translation release factors from Podospora anserina and analysis of their role during the life cycle.

Genetics - 1 Aug 1998

Gagny B, Silar P

Abstract excerpt

In an attempt to decipher their role in the life history and senescence process of the filamentous fungus Podospora anserina, we have cloned the su1 and su2 genes, previously identified as implicated in cytosolic translation fidelity. We show that these genes are the equivalents of the SUP35 and SUP45 genes of Saccharomyces cerevisiae, which encode the cytosolic translation termination factors eRF3 and eRF1,...

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Identifiers

PMID: 9691035
DOI: 10.1093/genetics/149.4.1763
PMCID: PMC1460253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

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Identification of the genes encoding the cytosolic translation release factors from Podospora anserina and analysis of their role during the life cycle.PMID 9691035Read ↗

N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination.Semantic proximity Read ↗

Cytosolic ribosomal mutations that abolish accumulation of circular intron in the mitochondria without preventing senescence of Podospora anserina.Semantic proximity Read ↗

Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae.Semantic proximity Read ↗

In Aspergillus nidulans the suppressors suaA and suaC code for release factors eRF1 and eRF3 and suaD codes for a glutamine tRNA.Semantic proximity Read ↗

Increased longevity of EF-1 alpha high-fidelity mutants in Podospora anserina.Semantic proximity Read ↗

Informational suppressor alleles of the eEF1A gene, fertility and cell degeneration in Podospora anserina.Semantic proximity Read ↗

N-terminal extension of Saccharomyces cerevisiae translation termination factor eRF3 influences the suppression efficiency of sup35 mutations.Semantic proximity Read ↗

The role of N-terminal domain of translational release factor eRF3 for the control of functionality and stability in S. cerevisiae.Semantic proximity Read ↗

Molecular dissection of translation termination mechanism identifies two new critical regions in eRF1.Semantic proximity Read ↗

Depletion in the levels of the release factor eRF1 causes a reduction in the efficiency of translation termination in yeast.Semantic proximity Read ↗

C-terminal domains of human translation termination factors eRF1 and eRF3 mediate their in vivo interaction.Semantic proximity Read ↗

Identification of translational release factor eRF1a binding sites on eRF3 in Euplotes octocarinatus.Semantic proximity Read ↗

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