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Article

A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans.

Genetics - 1 Jul 1996

Murakami S, Johnson T E

Abstract excerpt

A variety of mechanisms have been proposed to explain the extension of adult life span (Age) seen in several mutants in Caenorhabditis elegans (age-1: an altered aging rate; daf-2 and daf-23: activation of a dauer-specific longevity program; spe-26: reduced fertility; clk-1: an altered biological clock). Using an assay for ultraviolet (UV) resistance in young adult hermaphrodites (survival after UV irradiation),...

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Identifiers

PMID: 8807294
DOI: 10.1093/genetics/143.3.1207
PMCID: PMC1207391

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