Article
Invertebrate gerontology: the age mutations of Caenorhabditis elegans.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 1996
Lithgow G J
Abstract excerpt
Ageing is a complex phenomenon which remains a major challenge to modern biology. Although the evolutionary biology of ageing is well understood, the mechanisms that limit lifespan are unknown. The isolation and analysis of single-gene mutations which extend lifespan (Age mutations) is likely to reveal processes which influence ageing. Caenorhabditis elegans is the only metazoan in which Age mutations have been...
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